Physicochemical properties in relation to biological action, Unit-I B.Pharm 4th Semester Notes PDF

 

  • Introduction to Medicinal Chemistry
  • History and development of medicinal chemistry
  • Physicochemical properties in relation to biological action
  • Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation, Bioisosterism, Optical and Geometrical isomerism.
  • Drug metabolisam
  • Drug metabolism principles- Phase I and Phase II. 
  • Factors affecting drug metabolism including stereo chemical aspects



  • Introduction to Medicinal Chemistry

    History and Development of Medicinal Chemistry

    Physicochemical properties in relation to biological action

    • Ionization
    • Solubility
    • Partition Coefficient
    • Hydrogen bonding
    • Protein binding
    • Chelation
    • Bioisosterism
    • Optical and Geometrical isomerism

















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