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Pharmaceutical Organic-chemistry-II All Unit Notes Free PDF Download

Organic-chemistry-II All Unit Notes

BPharmacy, 3rd Semester, Notes

Free PDF Download


Content:

UNIT I: Benzene and its derivatives

Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel’s rule
Reactions of benzene - nitration, sulphonation, halogenationreactivity, Friedelcrafts alkylation- reactivity, limitations, Friedelcrafts acylation. 
Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction 
Structure and uses of DDT, Saccharin, BHC and Chloramine

UNIT II: Phenols, Aromatic Amines

Phenols: Acidity of phenols, effect of substituents on acidity, qualitative tests, Structure and uses of phenol, cresols, resorcinol, naphthols 
Aromatic Amines: Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts

UNIT III: Fats and Oils

Fatty acids – reactions.
Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils
Analytical constants – Acid value, Saponification value, Ester value, Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and principle involved in their determination.

UNIT IV: Polynuclear hydrocarbons

Synthesis, reactions, Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives

UNIT V: Cycloalkanes

Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only

UNIT VI: Polycyclic Aromatic Hydrocarbons

UNIT I: Benzene and its derivatives













UNIT II: Phenols, Aromatic Amines











UNIT III: Fats and Oils







UNIT IV: Polynuclear hydrocarbons



UNIT V: Cycloalkanes





UNIT VI: Polycyclic Aromatic Hydrocarbons





 

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